Clinical, Radiographical and Antibacterial Evaluation of Acemannan Sponge and Tri-Mix Used in Treatment of Non Vital Primary Molars

Sara Gonna, Rehab Foad Ghouraba, Radwa Eissa, Amal Kabbash, Akira Yagi, Nancy Mohamed Metwally


Aim: The present study was conducted to compare effects of acemannan and 3 Mix antibiotic (ciprofloxacin, amoxicillin and metronidazole) as pulpotomy in non-vital primary molars. And assess the antibacterial effect of acemannan and 3 Mix.

Materials and Methods: Aloe vera gel high molecular weight fractions (AHM) containing native ingredients of polysaccharide (acemannan) and glycoprotein (verectin) were obtained by using the patented hyper dry system after washing out coloured materials with running water from Aloe vera gel slurry. Twenty healthy children aged from four to eight years, they were selected from patients attending outpatient clinic of Pediatric Dentistry department. Each child had at least bilateral non vital lower primary molar indicated for non -vital pulpotomy. Non vital pulpotomy was done in both groups; where group I treated by 3Mix antibiotics, while AHM, acemannan used in group II. The study cases were recalled after three, nine and twelve months for clinical and radiographic evaluation.

Results: the overall clinical and radigraphical success rate of acemannan group was 82%, while 3mix antibiotic group was 18%. Fruther more, group 2 AHM showed better improvement in intra-radicular bone density with treatment than group I 3trimix which was statistically significant p > 0.05.

Conclusion: The acemannan showed higher clinical and radiographic success rate compared to 3mix antibiotic as a pulpulpotomy agent in non-vital primary molars. It can be considered as an acceptable biomaterial for non- vital pulp therapy of deep caries in primary teeth.


Acemannan; 3mix antibiotic; Primary teeth; Non-vital pulpotomy

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