A Rare Case of Giant Cell Tumor of Bone with Thoracic Extension with Horner's Syndrome

susmita kundu, Saswata Ghosh, Saurav Kar, Palash Nandan Dhara



Giant-cell tumor of the bone generally accounts for 4-5% of primary bone tumors and ~20% of benign bone tumors.[1] . It is characterized by the presence of multinucleated giant cells (osteoclast-like cells). Although classified as a benign tumor, GCTOB has been observed to metastasize to the lungs in up to 5% of cases [2]

Patients usually present with pain and limited range of motion caused by tumor's proximity to the joint space. There may be swelling as well, if the tumor has been growing for a long time. Some patients may be asymptomatic until they develop a pathologic fracture at the site of the tumor. The symptoms may include muscular aches and pains in arms, legs and abdominal pain. Patients may also experience nerve pain which feels like an electric shock.

In a population based study of Horner’s syndrome in the pediatric age group, the incidence of Horner’s syndrome was estimated to be 1.42 per 100 000 patients younger than 19 years, with a birth prevalence of 1 in 6250 for those with a congenital onset

We are presenting a case of a 27 year old male patient who presents with right sided chest pain and cough for 3 months and absence of perspiration of 2 months which was ultimately proved to be a case of Giant cell tumor of bone with thoracic extension with Horner’s syndrome.


Key Words - Giant cell tumor of bone, Horner’s syndrome.

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