Association Between Serum Concentrations of 25-hydroxy Vitamin D3 and Severity of Liver Stiffness by Using Vibration-Controller Transient Elastography

Eskandar Hajiani, Pezhman Alavinejad, Saieed Mathinkhah, Zohreh Badiee, Seyed Jalal Hashemi, Abdol Rahim Masjedizadeh, Ahmad Kadkhodae

Abstract


AIM: To evaluate the association between serum concentration of 25-hydroxy vitaminD3 [25(OH) D] and liver stiffness severity based on vibration- controller transient elastography (VCTE) in patients with nonalcoholic fatty liver disease (NAFLD). METHOD: Sixty two patients with NAFLD enrolled the study from May 2012 to August 2013. The severity of liver stiffness evaluated by VCTE. The correlation between severity of liver stiffness and serum levels of 25 (OH) D, total cholesterol, triglyceride, Fasting plasma glucose, ALT and AST were investigated. RESULTS: There was no significant correlation between severity of liver stiffness and serum concentration of 25 (OH) D (P=0.388) whiles we found a significant correlation between serum AST level and severity of liver stiffness (P=0.0001). CONCLUSION: There is no correlation between serum concentration of 25 (OH) D and severity of liver stiffness using VCTE.

Keywords


Nonalcoholic fatty liver disease; Vibration- controller transient elastography; 25-hydroxy vitaminD3

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