Effectiveness of Indocyanine Green Fluorescence in Gastric Adenosquamous Carcinoma with Hepatic Metastases

Hiromi Ono, Mitsuo Kusano, Hitoshi Yokoyama, Haruyuki Yoshida, Hiraku Fukushima, Masato Kawakami, Mikio Okamura, Takanori Aoki, Naoki Asakage, Kimimoto Nagashima, Yasushi Danjo, Hideyuki Hayashi, Hiroshi Nishihara, Yuichi Shimizu, Tsuyoshi Shimamura


Gastric adenosquamous carcinoma is a rare-, mixed-type gastric cancer, that consists of both glandular and squamous cells. Herein, we present a case of a 92-year-old Japanese female transferred to our hospital due to syncope and anorexia. Multiple hepatic tumors were detected on abdominal computed tomography, and esophagogastroduodenoscopy revealed a submucosal tumor at the distal gastric antrum. Hence, submucosal and intravenous injections of indocyanine green (ICG) were performed preoperatively 3 days before surgery and intraoperatively, respectively. ICG fluorescence was detectable in the gastric tumor although no fluorescence signal was observed in the hepatic tumors. In the case described here, ICG fluorescence imaging served as a useful technique for securing surgical margins during gastric tumor resection.


Gastric adenosquamous carcinoma; Hepatic metastases; Indocyanine green fluorescence

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