Update in Liver Diseases with Pregnancy

Maher Shams


Liver disease in pregnancy encompasses a spectrum of diseases encountered during gestation and the postpartum period that result in abnormal liver function tests, hepatobiliary dysfunction, or both. It occurs in 3% to 10% of all pregnancies.Several disorders contribute to liver disease in pregnancy. These include diseases induced by the pregnancy such as acute fatty liver of pregnancy (AFLP) and intrahepatic cholestasis of pregnancy (IHCP), diseases that existed before pregnancy that could potentially flare during pregnancy such as autoimmune hepatitis and Wilson's disease, and diseases not related to the pregnancy but that could affect the pregnant woman at any time during gestation such as viral hepatitis.

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