Listeria Infection during Biologic Therapy: An Update

Giovanni Casella, Elisabetta Antonelli, Vincenzo Villanacci, Francesco Bachetti, Gabriele Torti, Maria Pina Dore, Gabrio Bassotti


The therapeutic use of biological agents such as anti tumor necrosis factor-alpha drugs carries on an ìncreased risk of reactivation of bacterial infections. Among these, listeriosis is a particularly dreadful infection in that may be associated with septic complications such as meningitis and encephalitis and a relatively high mortality rate. This article will discuss listeria infections in patients treated with biological agents.


anti-TNF alfa agents, biological therapy, inflammatory bowel disorders, listeriosis, sepsis

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