Stromal Vascular Fraction for Musculoskeletal Lesions

E. Carlos Rodriguez-Merchan, Carlos A. Encinas-Ullan


Several clinical studies appear to demonstrate that intra-tendinous injections of stromal vascular fraction (SVF) are safe and effective in athletes suffering from recalcitrant Achilles tendinopathy and chronic lateral elbow tendinopathy. It has also been reported that intra-articular SVF injections appear to be effective and safe for the treatment of knee osteoarthritis. Local application of SVF has also proven useful in chronic diabetic foot ulcers. Ready-to-use extracellular matrix/SVF gel appears to be a favorable therapeutic approach to facilitating articular cartilage regeneration in patients with chondral lesions. However, there are insufficient high-quality data to recommend SVF for athletes with sports soft-tissue knee injuries. Several experimental studies have suggested that SVF could be a good option to achieve bone regeneration. To confirm the usefulness of SVF in various musculoskeletal injuries and to recommend its routine clinical use, better designed studies are required.


Stromal vascular fraction; Osteoarthritis; Tendon healing; Bone regeneration; Cartilage regeneration

Full Text: PDF HTML


  • There are currently no refbacks.

Creative Commons License
This work is licensed under a Creative Commons Attribution 3.0 License.