Microangiopathic Hemolytic Anemia in Metastasized Signet Ring Cell Carcinoma: A Report of Three Cases

Tuba Yuce, Oğuz Kağan Bakkaloğlu, Murat Köse, Timur Selçuk Akpınar, Tufan Tükek


Systemic manifestations of gastric cancer related to paraneoplastic phenomena are rarely seen at initial presentation. We report three patients who presented with microangiopathic hemolytic anemia (MAHA) with initial symptoms of metastatic signet ring cell adenocarcinoma.


Gastric carcinoma; Microangiopathic hemolytic anemia; Plasma exchange; Paraneoplastic syndrome; Signet ring carcinoma; Bone marrow metastasis; Osteoblastic metastasis

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